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Sweetened Soft Drinks Linked to Higher Depression Risk, While Black Coffee May Offer Protection: Analysis of 2 Million Participants

Вживання солодких напоїв може збільшувати ймовірність депресії, натомість чорна кава може мати позитивний вплив на настрій. Photo: НВ — Техно

The Relationship Between Soft Drinks, Coffee, and Mental Well-Being

A comprehensive meta-analysis of 59 studies conducted across 22 countries and involving over 2 million individuals revealed a clear connection between consuming sugary soft drinks and an increased risk of depression. Specifically, intake of these beverages was associated with an 18% higher chance of developing depression. Conversely, drinking black coffee—with little to no sugar—appeared to reduce depression risk by about 13%. These findings were published in the August edition of the journal Depression and Anxiety.

The study also found that coffee consumption did not significantly affect anxiety or stress levels. However, adolescents consuming more than 25 grams of sugar daily from soft drinks showed elevated anxiety and depression symptoms. Among women, drinking four cups of coffee each day lowered depression risk by 20%. Intake of 450-600 mg of caffeine daily was linked to a reduced depression risk compared to consuming 0-300 mg. Notably, higher caffeine doses did not provide additional benefits and could potentially worsen anxiety and stress.

How These Drinks Impact Mental Health

Sugary beverages increase inflammatory markers such as IL-6 and TNF-α and may promote insulin resistance, which leads to decreased levels of brain-derived neurotrophic factor (BDNF). Diets high in sugar disrupt cortisol rhythms and affect the hypothalamic-pituitary-adrenal axis. Low BDNF levels have been associated with a greater risk of depression. Research also linked artificially sweetened drinks to a 30% increased depression risk. Similar elevated risks were observed for:

  • sugary soft drinks (29% increase)
  • bubble tea (162% increase)
  • carbonated sodas (39% increase)
  • energy drinks (30% increase)

Researchers emphasize that most of the evidence comes from observational studies, which cannot definitively establish cause and effect.

"Nearly all research on this topic is observational and cross-sectional, making it difficult to draw firm conclusions. It’s possible that individuals experiencing stress or anxiety are more likely to consume sugary drinks," explained Andrew Odegaard.
"Currently, there is no officially defined 'safe' sugar limit specifically for mental health," added Jennifer Pallian.

Overall, these results highlight potential mental health risks associated with sugary soft drink consumption and suggest that black coffee might have protective benefits. However, definitive conclusions require further investigation. It is important to consider these drinks within the broader context of lifestyle and dietary patterns that influence mental well-being. Continued research will be essential to unravel the complex interactions between diet and mental health.

In light of the recent findings on the impact of beverages on mental health, it's intriguing to explore how decaffeinated coffee may enhance cognitive functions by influencing gut microbiota. Understanding these relationships could provide deeper insights into dietary choices that support mental well-being.