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Fish Oil Supplements Fail to Shield Against Alzheimer’s, Study Finds

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Дослідження виявило, що добавки риб'ячого жиру не запобігають розвитку хвороби Альцгеймера. Photo: НВ — Техно

New Research Questions the Role of Fish Oil in Alzheimer’s Prevention

According to НВ — Техно: A recent study from Keck Medicine at the University of Southern California, released on June 30, challenges the belief that fish oil supplements benefit individuals at higher risk for Alzheimer’s disease. Participants who took daily doses of docosahexaenoic acid (DHA) showed no improvement in memory tests, and brain scans revealed no slowdown in hippocampal shrinkage.

Americans spend over $1 billion annually on fish oil supplements. The study focused on people who rarely consumed fish, with nearly half carrying the APOE4 gene variant. Researchers randomly divided participants into two groups: one received 2,000 milligrams of DHA daily, while the other took a placebo. After six months, DHA levels in the cerebrospinal fluid rose by an average of 17%. However, after two years, those in the DHA group performed no better on memory and cognitive tests compared to the placebo group.

Brain imaging confirmed that the supplements did not slow hippocampal volume loss. Hussein Naji Yassin, one of the study’s authors, stated:

“The findings do not support using fish oil as a preventive measure against Alzheimer’s disease.”

He also emphasized that,

“while omega-3s are important for brain function, supplements alone do not provide the expected protective effect.”

Exploring Alternatives and Next Steps

Researchers suggest that omega-3s might be more effective when consumed as part of a Mediterranean diet. Scientists plan to investigate how the brain absorbs omega-3s and are working on developing drugs that could help the brain use these fatty acids more efficiently. The study authors highlight the importance of:

  • regular physical activity,
  • adequate sleep,
  • and a balanced diet for maintaining brain health.

This research casts doubt on the widely held assumption that fish oil supplements can prevent Alzheimer’s disease. It underscores the need for further studies focused on how diet and lifestyle factors contribute to cognitive health. Prioritizing exercise, sleep, and nutritious eating may prove more critical for reducing the risk of neurological conditions.

In light of these findings, it is crucial to explore other dietary factors that may influence brain health. Recent research has indicated a potential connection between vitamin C levels and brain volume, suggesting that essential nutrients play a significant role in cognitive function. Understanding the interplay between various vitamins and brain health could offer new insights into preventing cognitive decline.

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