Iodine and magnesium deficiency has affected human DNA: geneticists' discovery

Deficiency of trace elements and its impact on evolution

Scientists from University College London (UCL) have concluded that a lack of important trace elements such as iodine, magnesium, and iron can have a significant impact on human evolution and leave a mark on its DNA. The results of the study were published in The American Journal of Human Genetics (AJHG).

Researchers analyzed genes responsible for processing 13 key minerals and discovered changes in the genes that regulate their absorption in populations with a deficiency or excess of trace elements. These genes underwent positive selection, indicating the establishment of gene versions that help the organism adapt to the mineral imbalance.

Adaptation to conditions of deficiency and excess

Iodine deficiency and growth. Genetic adaptations to iodine deficiency have been found in the Mbuti people of Central Africa. Excess magnesium and toxicity. In South and Central Asia, changes in genes related to magnesium characteristics serve as protection against toxicity.

Project leader Jasmine Ries noted that adaptation to trace elements plays a crucial role in human history. The study confirms the deep connection between the environment and genetic heritage.

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The research by UCL scientists confirms the impact of trace element deficiency on the human genome and shows the importance of adaptation to conditions of deficiency and excess of various elements. By analyzing genes related to mineral metabolism, scientists discovered changes in genes that indicate the organism's adaptation to mineral imbalances. Such research is an important step in understanding the impact of the environment on genetic heritage and human evolution.